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我国埃博拉疫苗进入临床
文章来源:中国医药化工网    添加人:admin    添加时间:2016/12/8 15:45:15
 

  今天从军事医学科学院获悉:由该院生物工程研究所陈薇团队自主研发的重组埃博拉疫苗通过国家、军队联合评审,获得临床批件,将于本月开展人体试验。这是中国第一个、继美国和加拿大之后世界第三个进入临床试验的埃博拉疫苗,是全球首个2014基因突变型埃博拉疫苗。

  据悉,今年西非埃博拉疫情感染者已达17900多例,死亡6300多例,占1976年以来感染总数和死亡总数的80%和88%。中国工程院院士沈倍奋、陈志南、徐建国等17位专家评审后认为,2014基因型埃博拉病毒是1976年以来发生变异速度最快的,基因同源性为97.2%,且第一次“走出”非洲,到达欧洲和美洲。

  陈薇团队研发的疫苗不仅防控针对性最强,而且是全球首创冻干粉剂型,37摄氏度环境下可稳定2周以上,具备大规模生产技术条件,适合疫苗冷链条件难以保障的西非热带地区广泛使用。国外正在进行临床研究的埃博拉疫苗均为1976基因型液体苗,需零下80摄氏度保存和运输。

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